$10mil Competitive Research Programme over 5 years, by National Research Foundation
Genes encode for proteins which, together with environmental factors, lead to the metabolite inventory of an organism. Lipids are a critically important class of metabolites, yet many functions remain poorly understood, in particular at the molecular level.
Lipid research has made great strides with recent developments: Firstly, genetic and cell biological research has provided new insights into molecular mechanisms of lipid action. Secondly, deregulated lipid metabolism is increasingly shown to play an important role in numerous human diseases. Thirdly, novel tools for lipid detection being developed very rapidly.
It should be stressed that lipidomics (systems level scale analysis of lipids and their interacting factors) is a discipline which, due to its focus on lipids, is intrinsically allied with many other fields of research. Hence, a research programme in lipidomics will develop its full potential best if integrated with other fields such as life sciences, nutritional sciences or environmental sciences - both academic as well as corporate settings.
Development of novel (lipid based) biomarkers are a key focus in our group:
- Ovarian and gastric cancers
- Neurodegenerative Diseases: Alzheimer's disease, stroke and schizophrenia
- Inflammatory disorders: Rheumatoid Arthritis and Systemic Lupus Erythematosus (SLE)
- Infectious Diseases such as Tuberculosis and Dengue fever
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