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NMRC Translational & Clinical Research (TCR) Flagship Programme

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Aim

The TCR Flagship Programme Grant hopes to bring together the best complementary research strengths in hospitals and national disease centres, universities and A*STAR Research Institutes to focus on disease or research themes of strategic importance. It aims to integrate, coordinate and leverage on the full spectrum of research capabilities in Singapore from basic science to clinical research in an "all-the-way" fashion. The programme should seek to facilitate the discovery and application of basic science ideas relevant to the advancement of health, and provide productive platforms for collaboration with top overseas research institutions and industry. Collaboration across institutions is encouraged 

The grant call is open to all types of bench to bed research proposals, with no restrictions to any specific disease areas.

For more information, please visit NMRC Website

 

Funding Information

 

Type Capped Amount Maximum Duration
 Tier 1 $9M inclusive of indirect cost 5 years
Tier 2 $25M inclusive of indirect cost 5 years

 

Kindly note the Programme's Administrative Core will be funded from the grant award as direct costs.

 

If awarded, the grant will be fully administered by the Host Institution of the Lead PI.

 

 

Eligibility

 

Eligible Institutions

Public sector hospitals and national disease centres, as well as universities are eligible to apply for this programme.

A*STAR Principal Investigators (PIs) are encouraged to participate as co-investigators for their research component to be eligible for coverage by the programme budget.

 

Eligible Individuals to be the Principal Investigator

Well-qualified Clinician-Scientists are eligible to apply for the grant as a Lead Principal Investigator (Lead PI), whose role is to spearhead his/her proposed programme.

 

The CS should at the point of application fulfil the following requirements:


a) Clinically qualified (i.e. with MD/MBBS/BDS) and preferably with post-graduate clinical training and experience. For proposals involving patients the clinical PI or co-PI should be SMC registered; or the PI or co-PI should be able to demonstrate ability to access patients through SMC registered collaborators.

 

b) Hold a primary appointment in a local public hospital/public health institutions/national specialty centre/public universities/Academic Medical Centers and salaried by the institution.

 

c) Be an independent PI with a demonstrated track record of research as evidenced by the award of nationally competitive funding (international funding to be considered on a case by case basis) and substantial publication record in the past 3 years

 

d) Have a laboratory or clinical research program that carries out research in Singapore

 

e) Hold a minimum of 9 months employment with a local Singapore institution. Upon award, PI must agree to fulfil at least 6 months of residency in Singapore over a period of 1 calendar year

 

f) No outstanding reports from previous BMRC, NMRC grants, and other national grants.

 

Theme Principal Investigator 

Apart from fulfilling the criteria (b) to (f) listed above, the lead researcher should have the appropriate level of authority and the responsibility to direct each specific research theme being supported by the grant. He or she is responsible and accountable for the proper conduct of the specific research theme.

 

Co-Investigator (Co-I)

An individual involved in the scientific development and execution of the project. A co-Investigator typically devotes a higher percentage of effort to the project as compared to a collaborator and is considered a key personnel.

Co-I needs to hold at least an adjunct position in a local public institution.


Kindly note that researchers from overseas institutions or private companies can only participate as collaborators.

 

 

Selection Criteria

 

Selection will be on a competitive basis, incorporating both international peer review, and localized knowledge on the suitability and fit of the programme within Singapore's TCR initiative. The programme will be selected based on the evaluation criteria listed below:


i. (Key criteria) The programme must be led by an excellent CS PI (and co-PIs) whose strength must be in TCR;


ii. (Key criteria) Scientifically, the programme must be highly competitive, with a strong potential for the programme to be a leader internationally;


iii. The programme should ideally be "all-the-way" with investigative components starting from basic research through to clinical application;


iv. The programme must be optimally structured to strengthen and coordinate the full chain of research capabilities within the proposed disease area. The programme should build and establish strong collaborations with other entities, to coordinate and leverage on the best strengths in Singapore


v. Demonstrated commitment by the host institution (e.g. through co-funding) and industry collaboration would also be considered favorably


vi. Additional considerations will be given to programme which has higher potential in achieving economic returns and improving health outcomes.

 

Schedule of Annual Call

 

There is 1 call per year for 2011 - 2013. 

 

Application Procedures

 

Letter of Intent (LOI)

 

Kindly submit the following documents to NUHS, Tower Block Level 6, by 10 Jan 2013, Thursday at 12 noon, and forward a softcopy to Grant_RO@nuhs.edu.sg.  

  

Please indicate NUHS as the Host Institution. The header and footer should include the lead PI name and total funding amount.

 

 

NUS PIs NUH PIs Deadline

(1 original hardcopy duly signed by Lead PI & Theme PIs, 1 softcopy in a single Microsoft Word document including all annexes, pictures, tables, charts and attachments, if any & 1 scanned softcopy in a single pdf file

Please name the LOI in the following format:
TCR Dec12 LOI (Tier1/Tier2)-(Lead PI Name)_(Name of Host Institution)

 

(1 original hardcopy duly signed by Lead PI and HOD, and 1 softcopy in word format)

(1 original hardcopy duly signed by Lead PI & Theme PIs, 1 softcopy in a single Microsoft Word document including all annexes, pictures, tables, charts and attachments, if any & 1 scanned softcopy in a single pdf file)

Please name the LOI in the following format:
TCR Dec12 LOI (Tier1/Tier2)-(Lead PI Name)_(Name of Host Institution)

 

(1 original hardcopy duly signed by Lead PI and HOD, and 1 softcopy in word format)

10 Jan 2013 (Thu),       12 noon
 

 

Please refer to the attached Application Guide and the NMRC website for more information.

 

 

Contact Us

 
Mr Chia De Qing Tel:  6772 3708 Email:  medcdq@nus.edu.sg