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2017

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November 2017

More hypertensives here if S’pore adopts new rate


The stricter high blood pressure guidelines recommended by the American Heart Association is 130/80 versus the existing 140/90. Professor Tan Huay Cheem, Director, NUHCS said that there is no reason to reject these recommendations.

He shared with ST that cardiologists should still treat patients with stage 1 hypertension with lifestyle changes and start drug treatment only if he has multiple other risk factors (eg diabetes mellitus etc).

Prof Tan also said the 130/80 cut-off is for at least two readings done at home. The cut-off at clinics stays at 140/90 as anxiety tends to raise a person's blood pressure.

 

国大研究:控制血液化合物有助治疗癌症及心血管疾病


Researchers from National University of Singapore (NUS) have uncovered the secret behind how blood cells release a vital biological substance that is involved in essential processes like immune and blood vessel functions. This knowledge of the pathway by which blood cells release sphingosine-1-phosphate (S1P) carries broad implications for the treatment of cancer and cardiovascular diseases to open up new ideas.

This study was published in Nature on 18 October 2017.

Dr Long Nguyen, who is an assistant professor from the Department of Biochemistry at the NUS Yong Loo Lin School of Medicine (NUS Medicine), is the lead PI for this study. He reveals that the team is also working with A /Prof Mark Chan of NUHCS and Prof Chng Wee Joo of NCIS to discuss the application of the results in clinical practice.

 

Economy class syndrome' is a misnomer


Dr Yap Eng Soo, Consultant, Department of Haematology-Oncology, NCIS, shares that the main cause of venous thromboembolism (VTE) during flights is a combination of dehydration and immobility.  This could be why some studies have shown taking the window seat might make one more prone to VTE.   He adds that the class of travel does not matter as business class passengers have the same risk of VTE as those in economy class. Being immobile for long periods of time can put you at risk of blood clots or deep vein thrombosis (DVT).  This is why flying, especially in cramped conditions, has been associated with DVT.

 

Dangers of deep vein thrombosis: Don’t let blood clot in vein go untreated


Dr Yap Eng Soo, Consultant, Department of Haematology-Oncology, NCIS, shares that out of 100,000 patients who are hospitalised in Singapore, around 100 are estimated to have developed venous thromboembolism (VTE) as a result of hospitalisation. Being immobile for long periods of time is one of the most common risk factors for VTE, due to the slowing of the blood flow in the veins. Pregnant women are also at risk of developing VTE.  VTE can be prevented and treated with medication or with lifestyle modifications.


Gift from 63,257 Singaporeans to healthcare research


The opinion article introduced the landmark Singapore Chinese Health Study and some its significant findings. The more than 20 year old cohort study has contributed much to health research in Singapore, in areas ranging from cancer to nutrition.  The contributed article was written by Emeritus Professor Lee Hin Peng and Professor Koh Woon Puay from NUS SSHSPH.  

 

研究本地华族健康逾20年


The Singapore Chinese Health Study (SCHS), a large-scale research study helmed by the NUS Saw Swee Hock School of Public Health (SSHSPH), is the first population-based cohort study to be established in Singapore two decades ago. It is also one of the largest cohort studies based in Asia. The Study was established with a 63,275-member strong cohort of Chinese men and women, aged 45-74 years, who were recruited between April 1993 and December 1998.

The founding principal investigators of the Study are Dr Mimi Yu, who has retired from academia since 2009, and Emeritus Professor Lee Hin Peng from SSHSHP. Dr Mimi Yu will be presented with the inaugural Distinguished Service Award by the NUS Saw Swee Hock School of Public Health in recognition of her contributions to the establishment of the Study.  

 

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October 2017

用拉链失灵原理 治疗儿童白血病


The article is contributed by Associate Professor Allen Yeoh, Head & Senior Consultant, Division of Paediatric Haematology-Oncology, NCIS and NUH. He shared with readers on how leukaemia happened and worked, and using mercaptopurine to treat  leukaemia in children.


画水墨画预防失智?


The NUS Yong Loo Lin School of Medicine would be conducting a joint research study with the Shanghai Mental Health Center and Shanghai Jiaotong University to find out whether ink painting can prevent dementia. The study will commence next year and conducted over a period of three years. This is the first time that Singapore and China is studying mental health interventions together.  Dr Feng Lei, Department of Psychological Medicine, NUS Medicine, is leading the study.

 

两机构合作推出社区培训班改善中风病患记忆


Singapore’s first community-based brain health and memory training programme was launched on Friday (Oct 27) by non-profit organization, Stroke Support Station (S3) in partnership with NUHS. The programme will be led by the community, with guidance and support from medical professionals. The long-term aim is to enable stroke patients to live independently. 

 

怀孕八个月, 少妇突心脏肿


NUHCS patient, Ms Han Xiu Juan, was interviewed for this story relating to heart disease and pregnancy. Ms Han, who is 33 years old, shared her patient journey as a young mother diagnosed with heart failure during pregnancy, and how she went through treatment and recovered from the disease.

Dr Chan Wan Xian, Senior Consultant, Department of Cardiology, NUHCS, shared that the incidences of a woman diagnosed with heart failure during her pregnancy, is about 1 in 1000 live births (in Africa and Asia) and this condition is known as Peripartum Cardiomyopathy  and has increased attention in recent years. Heart failure can also occur in pregnancy due to many other causes such as when there is infection, uncontrolled high blood pressure, ischemic heart disease and other medical conditions.

This story is pitched in conjunction with Go Red@Clementi health screening event on 5 Nov.

医学生上门为年长者体检


Elderly residents of Kampong Glam will be assessed for frailty and mental health issues as well as chronic illnesses at the free health screenings by NUS Medicine students and involving the participation of their Nursing and Social Work counterparts. The Neighbourhood Health Service (NHS) is an annual community health screening that aims to identify residents in need. It focuses on the elderly and residents from lower income families living in rental blocks and reconnects them to the healthcare system.  Since its inception a decade ago, the NHS has touched the lives of more than 4,000 rental block residents in eight rental districts in Singapore. From offering just three screening modalities in its inaugural screening, the NHS has expanded its scope to more than 20 services, providing residents with a robust assessment of their health.

 

New study shows right way for diabetics


Putting off a healthy lifestyle or failing to take medication regularly is easy but the negative effects from such actions may well be irreversible, according to a new study by NUS. Assistant Professor Kavita Venkataraman from the NUS Saw Swee Hock School of Public Health said it shows it is not only important to control diabetes well, but it is also important to control it well over time. If doctors can identify and intervene early, the nasty effects can be mitigated, even in cases of high blood sugar levels.

 

Revolution in cancer care


A team of researchers pioneered a simple blood test that can detect a biomarker - a molecule that indicates certain processes taking place in the body - that is found in up to 70 per cent of all breast cancer patients who suffer a relapse. The team also discovered that early-stage breast cancer patients who have this biomarker are almost 40 times more likely to relapse within five years, compared with those who do not. Research on the biomarker was led by A*STAR’s Genome Institute of Singapore, Tan Tock Seng Hospital (TTSH) and the National University Health System (NUHS), with international collaborators from Denmark and the United States.

 

总裁刘以仁:服务西部百多万人口. NUP涵盖各年龄段医疗需求


In his interview with Zaobao, Dr Lew touched on a wide range of topics, including his vision for NUP, serving the healthcare needs of the population in the Western region of Singapore, collaborating with other institutions within the NUHS to provide more coordinated care, and developing future-ready healthcare professionals. He also talked about working with NUS Medicine to enable medical students to have earlier exposure to Family Medicine.

 

本地研发新血液测试 或可预测乳癌复发风险


Local researchers have identified biomarkers that are significantly associated with breast cancer recurrence. The possibility of cancer recurrence among early breast cancer patients, if tested positive with this biomarker, was nearly 40 times higher. Based on this discovery, a simple and easy- to- use blood test would be developed in future for clinical diagnosis and treatment of breast cancer patients. 

Co-author Associate Professor Lee Soo Chin, Head and Senior Consultant, Department  of Haematology-Oncology, NCIS, shared that the discovery of this biomarker was expected to help patients avoid prolonged exposure to radiation released by computer tomography and developed more targeted therapies.

The study was led by the Genome Institute of Singapore, Tan Tock Seng Hospital, and NUHS.  Researchers from Denmark and the United States are also involved in the study. The results of this study have been published in Nature Medicine.

 

降胆固醇新药减患病风险


A newly-developed drug, Alirocumab, which has recently been approved for use in Singapore may aid in the fight against cholesterol, can be taken as complement to statins or prescribed alternative medicine. Compared with the clinically widely used statins, this new drug can effectively reduce bad cholesterol within two years, thereby reducing the risk of cardiovascular disease and stroke patients.

In the media briefing, Associate Professor Poh Kian Keong, Senior Consultant, Department of Cardiology, NUHCS, shared findings of the study “Options to manage LDL-C and CV risk”, and also shared findings of the Odyssey Clinical Trials Programme. Prof Tai E Shyong of NUH and NUS Saw Swee Hock School of Public Health shared the study about “Genetics of hyperlipidaemia in Asian”.

 

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September 2017

浅谈中医药在介入心脏治疗领域的应用


Professor Tan Huay Cheem, Director of NUHCS shared his thoughts on the application of traditional Chinese medicine in the field of heart disease treatment especially in interventional cardiology.

Prof Tan concluded that as a doctor trained in western medicine, he still had some hesitation towards Traditional Chinese Medicine (TCM) as there were many international studies on TCM which might not be scientific. Prof Tan wrote that more TCM research was needed and TCM should be incorporated with western medicine to achieve the best benefits of both.

 

Keeping weight on is part of body’s defence mechanism


In this article, Professor Tai E Shyong, who leads the metabolic disease summit research programme at NUHS, explains why the body’s regulatory system against weight loss means that we need to work harder and harder to continue to lose weight. Prof Tai, who is also from the department of medicine at National University of Singapore Yong Loo Lin School of Medicine, advises readers not to forget that what they drink also adds to their calorie intake and that preventing weight gain is actually easier than losing weight.

 

Harnessing innovation in public health


A contributed article by Dr Heidi Larson, Director and Dr Neisha Sudaram, Research Fellow of The Vaccine Confidence Project (VCP) at the London School of Hygiene & Tropical Medicine, UK outlined the role of innovation in healthcare by giving the example of how vaccines have helped tremendously in medicine. As part of the article, the authors referenced the 2nd Raffles Dialogue, which they had participated in. The event was hosted last week by the National University of Singapore schools of medicine, public health and public policy, and NUHS, and focused on "The Critical Role of Innovation" in the context of the broader theme of "Human Well-being and Security in 2030".

 

研究:风险高达25% 幼儿肥胖都是父母超重惹的祸


A study lead by NUHS, A*STAR and KKH, show that the weight of parents is a key factor affecting the weight of young children. Generally, the mother is believed to be the culprit leading to obesity. But a local study shows that the father's weight will also increase the risk of overweight children. If the parents are overweight, the risk of overweight children is as high as 25%.

Associate Professor Lee Yung Seng, Head, Department of Paediatrics and Senior Consultant, Division of Paediatrics Endocrinology, NUH gave an interview regarding this GUSTO study.

 

How AI can help healthcare.


A contributed article, co-written by Assistant Professor Feng Mengling (NUS Saw Swee Hock School of Public Health) and Assistant Professor Ngiam Kee Yuan (Deputy Chief Medical Information Officer, NUHS), outlined how artificial intelligence is helping to manage big data and information flows in healthcare in various areas e.g. improving diagnosis, predicting complications, in preventative medicine and bringing together multidisciplinary teams together to solve healthcare challenges. The writers also urge doctors to learn how to use AI tools to enhance their treatment and care of patients.

 

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August 2017

Research on behaviour, targeted messaging may help Singapore's war on diabetes: Experts


With many countries facing the challenge of rising levels of diabetes, developing different strategies to target specific sectors of the population is emerging as an effective weapon. Prof Tai E Shyong, Senior Consultant, National University Hospital and lead for the NUHS Metabolic Disease Summit Research Programme (SRP) gave examples of these strategies and how a better understanding of communities would be essential in dealing with diabetes. 

 

Is acute aortic dissection the most dangerous heart disease


Professor Tan Huay Cheem, Director of the National University Heart Centre Singapore shared about acute aortic dissection, symptoms of the disease and how to diagnose and treat this cardiovascular disease. According to a study, the main cause of acute aortic dissection is hypertension and the average age of patient is 62 years old.

 

The Heart of Service


As part of NUP’s recruitment campaign, Dr Chua Ying Xian was profiled and he elaborated on his experience as a family physician at Pioneer Polyclinic and why it is rewarding.

 

Putting Singapore on map of medical advances


Prof Lee Eng Hin, Chief Advisor for NUHS’ Summit Research Programmes contributed an article about the current Singapore research environment in Singapore and how it is conducive for nurturing clinician scientists. He gave examples of how the formation of academic medical centres such as the National University Health System (NUHS) and research initiatives like NUHS’ Summit Research Programmes have created an environment for clinician scientists to thrive. He urged young talent to take up the clinician scientist role and lead the charge in building a healthier future.  

 

Found - Molecule that stops heart from self-healing


Scientists from A*STAR’s Genome Institute of Singapore (GIS) and the National University Health System (NUHS) have discovered a chemical compound in mice that prevents heart muscle cells from repairing themselves. If it can be blocked, heart muscle cells can regenerate, like skin cells, and the heart may be able to heal itself. The study was led by Associate Professor Roger Foo, principal investigator at GIS, and at NUHS' Cardiovascular Research Institute as well as senior consultant at the National University Heart Centre, Singapore.

 

Caring for patients at home through the phone


Hospitals, polyclinics turn to remote services to better track their conditions, reduce visits by their patients. The National University Health System (NUHS) plans to add to its existing services to monitor patients' medical conditions in their own homes later this year.

 

 

Love of food, lack of activity leave Singaporeans vulnerable to diabetes


Assistant Professor Mary Chong and Associate Professor Rob M van Dam, from NUS Saw Swee Hock School of Public Health, wrote a commentary on diabetes and the possible reasons Singaporeans were may be particularly vulnerable to diabetes. They opined that this was due to the abundance of easily accessible and mostly affordable food and physical inactivity.  

 

Use of alternative medicine does more harm than good: Studies


Two studies acknowledged the use of complementary and alternative medicine (CAM) by patients to get well and concluded that CAM may sometimes do more harm than good.  One of the studies is led by Dr Chong Wan Qin, an Associate Consultant Oncologist with the National University Cancer Institute, Singapore (NCIS) shows that if there are decision aids, it may reduce the use of CAM among cancer patients and encourage them (the patients) to discuss the use of CAM with their oncologists, while undergoing chemotherapy treatment.

 

He quit smoking after finding out he had cancer


An NCIS patient, Mr Koh Teck Hoe, a colorectal cancer survivor, adopted a healthier lifestyle and quit smoking after finding out that he had cancer. Dr Tan Ker Kan, a consultant with the division of surgical oncology (colorectal surgery) at the National University Cancer Institute Singapore, advised  people to go for early screening as it would improved survival outcomes.


Thryoid Cancer


Dr Ngiam Kee Yuan , Consultant, Division of Surgical Oncology (Thyroid and Endocrine Surgery), NCIS shared about thyroid cancer and its treatment options.


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July 2017

Chemo at home helps cancer patients cut disruptions to daily life


APN (Dr) Lee Yee Mei, Assistant Director of Nursing and Assistant Nurse Clinician Chen Litang shared about our chemotherapy home-care programme. A patient’s caregiver, Mdm Syaida also shared her positive feedback regarding the programme. 

 

Exercise Therapy Centres to be set up in hospitals


An Active Centre will open next year at Alexandra Hospital. This is a partnership between SportSG and NUHS, providing exercise therapy for patients from its chronic and metabolic disease clinics to complement the usual medical treatment.

 

 

Cure for hepatitis B around the corner


Prof Lim Seng Gee (Senior Consultant, Division of Gastroenterology & Hepatology) shared an opinion article on the conditions and cure for hepatitis B, and how a cure was close at hand. Prof Lim commented on the spread and dangers of the disease and how a research study at NUH is seeking 2,500 volunteers with chronic hepatitis B to help gain better insights on the disease. A panel of blood tests, ultrasounds and other scans are provided at no cost to the patients for five years.

 

Coffee, a health drink or an unhealthy addiction


Associate Professor Rob M van Dam from NUS Saw Swee Hock School of Public Health, a member of the National University Health System, wrote a commentary on the pros and cons of coffee consumption. His expert opinion comes on the back of the findings of a recent study showing that those who drank about three cups a day tended to live longer than non-coffee drinkers.

 

 

New Polyclinic in Jurong lives up to its Pioneer name


The newly opened Pioneer Polyclinic - the first new polyclinic to open in more than 10 years - featured several pioneering features. These new features included an automated pharmacy registration process, and a system to pair its patients with chronic diseases, like diabetes, with a dedicated care team to improve the care that these patients receive. Dr Lew Yii Jen, Chief Executive of National University Polyclinics said that the polyclinic was ramping up the number of care teams to take care of as many as 30,000 patients with chronic conditions in about three years’ time.


New way to detect heart failure that’s hard to diagnose


A local study by the NUHCS on about 657 women and men, discovered the thymosin beta-4 (TB4) protein is elevated in women with a form of heart failure called preserved ejection fraction or HPpEF. The protein could also be used clinically as a biomarker in the future to predict if a patient is responding to treatments.

Assistant Professor Chester Drum, Consultant Cardiologist, NUHCS, is the lead investigator in this study.

 

 

Blood tests may not detect cancer earlier


Many people have the misconception that they need to do cancer or tumour marker tests to screen for cancer. A blood-cancer marker is a substance produced in the body by cancerous cells. It is also made by some normal cells, although the levels tend to be much higher when there is cancer. 

However, such tests are generally considered to be of uncertain value. Dr Lim Siew Eng, a senior consultant at the haematology-oncology department at the National University Cancer Institute, Singapore, shares why blood test should preferably  not be used in place of recommended screening tests for cancer.

 

 

 

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June 2017

Breast, Prostate Cancers rising sharply in Singapore


Breast and prostate cancer incidences have risen two-fold and five-fold, respectively over the past 40 years, based on the latest cancer registry report. However, better treatment regimes have also resulted in better survival rates for breast cancer patients. Overall, colorectal cancer is still the top cancer in Singapore. Dr Tan Ker Kan, Consultant, Division of Surgical Oncology (Colorectal Cancer), NCIS, is quoted sharing that colorectal cancer is affecting patients younger than 55 years old. Dr Tan’s study on “Young colorectal cancer patients often present too late” was shared with the Straits Times. Dr Tan explains that there is an urgent need to raise awareness among younger adults and it is possible to have colorectal cancer at a younger age and to seek medical help earlier, as early detection means better outcomes. 

 

“Should you eat before you exercise”


空腹运动消脂迷思

Conventional advice tells us to eat before exercising. However, many believe that working out on an empty stomach promotes fat burning, and consequently more effective weight loss. Medical experts in physiology and nutrition as well as fitness trainers explain that while exercising in a fasted state does help with burning fat, it is crucial to have adequate food intake prior to a workout to ensure that the body has enough energy to sustain itself – this is especially so for intensive workouts. The key to effective weight loss lies in controlling one’s food intake while taking the type of workout and the energy spent as a guide.

 

The latest guide to preventing and treating hyperlipidemia


防治高血脂症的最新指南 (The latest guide to preventing and treating hyperlipidemia)

Professor Tan Huay Cheem, Director of the National University Heart Centre Singapore, shared the latest guide by MOH on prevention and treatment of hyperlipidemia and urged readers to follow the MOH guidelines if they are unsure.

He cautioned readers not to trust "false news" on the internet from the many so-called “medical authority” advocating heart disease patients not to take statins to control their cholesterol levels. Many of these “false news” exaggerate the side effects of statins which claim to lead to kidney failure, dementia and so on.

 

There are numerous large-scale clinical studies which have confirmed that statins are prescribed for patients to lower their total cholesterol levels and reduce their risk of a heart attack or stroke. Their side effects are generally well tolerated.

 

 

 

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May 2017

Private health sector urged to digitise records


Speaking at the National Health IT Summit 2017, Health Minister Gan Kim Yong urged the private health sector to speed up digitising patients' health records and be part of a national scheme to share patient information with other doctors when needed. In his speech, he also praised NUHS for using data to identify cost- effective clinical practices, reduced unnecessary variations and improved both cost and clinical outcomes. Associate Professor James Yip and Dr Keith Lim lauded at the event, winning the award for NUHS Value Driven Outcome in the category IT Excellence : Beyond Quality to Value. 

 

 

DocTalk: Zipper malfunction translated into cures


Associate Professor Allen Yeoh, discussed about childhood leukaemia and chemotherapy drug, mercaptopurine.

 

First-degree relatives must do early colonoscopy


First degree relatives of cancer patient are at increased risk of colorectal cancer as compared to the general population. Colonoscopy rates amongst the first degree relatives remain dismal. The study by Dr Tan Ker Kan, Consultant, Division of Surgical Oncology (Colorectal Cancer), NCIS explores the various issues amongst the patients and their first degree relatives precluding their adoption of screening colonoscopy.

 

 

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April 2017

Prevention is always better than cure when it comes to your heart


You have signed up for a marathon and you aim to complete the race. You have set your targets and that should include going for pre-participation screening (PPS).

PPS is important as it aims to detect heart conditions that are potentially life-threatening, especially during physical activities.

 

New treatment extends the life of late-stage stomach cancer patients


NCIS has come up with a new treatment, using Intraperitoneal Chemotherapy for patients with late-stage stomach cancer. Under this targeted treatment, the chemo fluid will be inserted directly into the stomach area. Of the 22 patients who participated in the clinical trial, more than half of the patients had their lifespan extended more than 16 months, which was comparatively longer than the usual three to six months for such patients undergoing the traditional treatment. Prof Jimmy So, Head & Senior Consultant, Division of Surgical Oncology, National University Cancer Institute, Singapore (NCIS) will share more details here.

 

Science Briefs - Cardiac Disease-Dementia link found


A team of cardiovascular and brain researchers from the NUHS have uncovered a link between cardiac diseases and tiny brain lesions commonly found in patients with cognitive impairment or dementia. They found that the presence of tiny brain lesions, called cerebral microinfarcts (CMIs), was strongly associated with cardiac disease and blood cardiac biomarkers - molecules or genes linked to the condition. Associate Professor Christopher Chen, director of NUHS' Memory Ageing and Cognition Centre said the findings suggest that the development of these tiny brain lesions, which are closely linked to diseases like dementia, may be caused by chronic heart problems and vascular disease. Apart from signalling problems with the heart, cardiac biomarkers are also indicators of injury to circulatory and blood vessel systems in other organs, for example the brain, said Prof Arthur Mark Richards, director of NUHS' Cardiovascular Research Institute.

 

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March 2017

Drug combo doubles myeloma survival rates


A first-of-its-kind multi-centre, multi-country clinical trial on multiple myeloma cancer established by the National University Cancer Institute, Singapore (NCIS), has produced positive outcomes, benefiting patients not just in Singapore but in Asia. The first clinical trial, which is called AMN 001, is initiated by NCIS is for patients who failed available standard treatment. The results of the trial showed that about 50% of the patients have their survival rates prolonged to 14 months or longer. This is more than double their previous average survival rate in this type of patients.

 

Making it harder for youth to light up


Prof Chia Kee Seng, Dean, Saw Swee Hock School of Public Health, commented on how youth are more susceptible to nicotine dependency and supported the move to raise the minimum legal age for smoking from 18 to 21. The Health Ministry outlined several reasons for taking this step, including the fact that regular tobacco use is usually established between 18 and 20 years of age.  

预防失智症从现在开始


zbNOW carried an advertorial by the Ministerial Committee of Ageing (MCA) on understanding dementia. It also carried an accompanying article on how the onset of dementia can be prevented or delayed through a balanced diet, regular exercise, regular social interaction and maintaining an active mind. Prof Kua Ee Heok, Senior Consultant Psychiatrist, NUS Yong Loo Lin School of Medicine, and Dr Ng Li-Ling, Senior Consultant, Psychological Medicine, Changi General Hospital (CGH) emphasised the importance of early prevention and intervention to lower one’s risk of dementia. 

日饮一杯鲜奶能降低高血压风险


Research based on data from the Singapore Chinese Health Study, with over 37,000 Chinese male and female participants, has found that participants consuming the highest levels of dairy products were 7% less likely to be diagnosed with hypertension than those consuming the least, and daily milk drinkers (mostly one glass per day) were 6% less likely than people consuming no milk, to be diagnosed with hypertension. The study, led by Prof Koh Woon Puay from Duke-NUS Medical School and NUS Saw Swee Hock School of Public Health, was published in the February 2017 issue of the Journal of Nutrition.

Addressing the unmet needs of high risk cholesterol patients


The Dyslipidemia International Study (DYSIS), which was carried out in thirty countries worldwide, looked at the level of low-density lipoprotein cholesterol (LDL-C) target attainment in patients on lipid-lowering therapy. DYSIS II, which was also carried out in Singapore, studied LDL-C targets achievement in patients with acute coronary syndrome (ACS) and stable coronary heart disease (CHD).

 

Associate Professor Dr Poh Kian Keong, who was one of the investigators of DYSIS and Clinical Director of Research, Department of Cardiology, National University Heart Centre (NUHCS), comments on the results of DYSIS and what this means for patients in Singapore. This may call for more effective lipid lowering therapies, such as combination therapy in order to improve patients’ outcomes.

 

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February 2017

Torching food popular, but overcooked food is harmful


A new health campaign in the United Kingdom seeks to raise public awareness  on how browned food generally contains cancer-causing chemicals and poses health risks. As the trend of torching food catches on in Singapore, Professor Jeyakumar Henry, Director of the Clinical Nutrition Research Centre, a collaboration between the A*STAR’s Singapore Institute for Clinical Sciences and the National University Health System, explained to readers the science behind charred foods, its possible effects on health, and gave advice on eating healthier.

 

須及早做乳癌基因檢驗


It is important for women with a family history of cancer to go testing early and identify if they have a BRCA mutation, so that they can go for regular screening and intervene necessarily.  According to Dr David Tan, Consultant, Department of Haematology-Oncology, National University Cancer Institute, Singapore (NCIS), genetic testing was beneficial not only for the patient, but also for the patient’s family. This is because if a person is tested to have a BRCA mutation, her children will also have a 50% chance of having the mutation as well. In such cases, it would be ideal to have early screening and detection to minimise the onset of cancer.

 

A shot in the arm for HFMD vaccine research


Singapore is one step closer to developing a vaccine against hand, foot and mouth disease (HFMD).

 Thanks to a comprehensive study of the HFMD virus, enterovirus 71, led by Assoc Prof Justin Chu of NUS Yong Loo Lin School of Medicine, who uncovered how the virus replicates within cells.

 The findings pave the way for vaccine development against the disease, which is highly prevalent here. In 2016, 42,154 people have been affected by HFMD. From the start of the year until 11 Feb, a total of 3,421 people have contracted the virus.

 

心血管病疗法将有新改变


According to Prof Tan Huay Cheem, Director of National University Heart Centre, Singapore, treating cardiovascular disease will have new changes with subcutaneous injection of drugs soon. Subcutaneous injection of drugs for heart diseases will be more convenient and it can be developed into a "painless" state, easier for patients to adapt. There will be new generation of stents and pacemakers which will be safer and more innovative for patients to use too. 

 

Silver Linings, even as childhood cancer rates rise


Childhood cancer has been on the rise in Singapore cancer and experts have referred to the theory of ‘ delayed infection’ hypotheses . It states that delayed exposure to infections due to an increasingly hygienic environment may affect how children’s immune system mature. Fortunately, progress made in cancer treatments  have made it possible for young patients to receive a more personalised treatment regimen with less side effects but an improved survival rate. 

 

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January 2017

Babies with eczema at higher risk of tooth decay


A recent GUSTO (Growing Up in Singapore Towards healthy Outcomes)  study led by the NUS Faculty of Dentistry, and the Singapore Institute for Clinical Sciences (SICS) of the Agency for Science, Technology and Research (A*STAR), uncovered the association between eczema in infants and the increased risk of tooth decay in early childhood. Tooth decay and eczema are among the most common childhood diseases, and the findings will give parents and caregivers of babies with eczema early warning in order to minimise the incidence of tooth decay in these children.

 

The Wonders Of Medical Research


Medical research may pave hope for acute leukaemia patients, thanks to stem cell transplants.  Dr Michelle Poon, senior consultant at the Department of Haematology-Oncology, National University Cancer Institute, Singapore, shared that with more research and selfless donors coming forward,  acute leukaemia patients may receive the priceless “gift of life” .

 

如何减低患肺癌风险?


Dr Ivan Tham, Head and Senior Consultant, Department of Radiation Oncology, National University Cancer Institute Singapore (NCIS) provided answers to a Lianhe Wanbao reader’s questions about lung cancer. The reader asked about the treatment for her 52-year-old husband, who was diagnosed with lung cancer, and if smoking and lung cancer were related.

 

与糖尿病作战 从自身开始


The article, written by Prof Tan Huay Cheem, Director of NUHCS, is the second part of his column about curbing diabetes and how diabetes can be linked to heart diseases. He shares that diabetes is caused by long-term bad eating habits and unhealthy lifestyle. Making adjustments to lifestyle changes such as more exercises, diet and weight control are the most basic aspects to combat diabetes. Diabetic patients with any suspicious cardiac symptoms, should seek medical advice as soon as possible.

 

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